Peng, H
mTORC1 enhancement of STIM1-mediated store-operated Ca2+ entry constrains tuberous sclerosis complex-related tumor development. [electronic resource]
- Oncogene Sep 2013
- 4702-11 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1476-5594
10.1038/onc.2012.481 doi
Adaptor Proteins, Signal Transducing
Animals
Calcium Channels--genetics
Calcium Signaling--physiology
Cell Line
Cell Line, Tumor
Cell Transformation, Neoplastic
Female
Fibroblasts
Humans
Kidney Neoplasms--genetics
Leiomyoma--pathology
Mechanistic Target of Rapamycin Complex 1
Membrane Proteins--physiology
Mice
Mice, Inbred BALB C
Mice, Nude
Multiprotein Complexes--physiology
Neoplasm Proteins--physiology
Neovascularization, Pathologic--physiopathology
ORAI1 Protein
Phosphorylation
Protein Processing, Post-Translational
RNA Interference
Rats
Recombinant Fusion Proteins--physiology
Stromal Interaction Molecule 1
TOR Serine-Threonine Kinases--physiology
Tuberous Sclerosis--genetics
Tuberous Sclerosis Complex 2 Protein
Tumor Necrosis Factor Receptor-Associated Peptides and Proteins--metabolism
Tumor Suppressor Proteins--physiology
Uterine Neoplasms--pathology