TY - GEN AU - Hickey,Christopher J AU - Schwind,Sebastian AU - Radomska,Hanna S AU - Dorrance,Adrienne M AU - Santhanam,Ramasamy AU - Mishra,Anjali AU - Wu,Yue-Zhong AU - Alachkar,Houda AU - Maharry,Kati AU - Nicolet,Deedra AU - Mrózek,Krzysztof AU - Walker,Alison AU - Eiring,Anna M AU - Whitman,Susan P AU - Becker,Heiko AU - Perrotti,Danilo AU - Wu,Lai-Chu AU - Zhao,Xi AU - Fehniger,Todd A AU - Vij,Ravi AU - Byrd,John C AU - Blum,William AU - Lee,L James AU - Caligiuri,Michael A AU - Bloomfield,Clara D AU - Garzon,Ramiro AU - Marcucci,Guido TI - Lenalidomide-mediated enhanced translation of C/EBPα-p30 protein up-regulates expression of the antileukemic microRNA-181a in acute myeloid leukemia SN - 1528-0020 PY - 2013///0225 KW - Adult KW - Animals KW - Antimetabolites, Antineoplastic KW - pharmacology KW - CCAAT-Enhancer-Binding Proteins KW - biosynthesis KW - Cell Line, Tumor KW - drug effects KW - Cytarabine KW - Frameshift Mutation KW - Gene Expression Regulation, Leukemic KW - Humans KW - Immunologic Factors KW - K562 Cells KW - Lenalidomide KW - Leukemia, Myeloid, Acute KW - drug therapy KW - Mice KW - Mice, Inbred NOD KW - Mice, SCID KW - MicroRNAs KW - Neoplasm Proteins KW - Point Mutation KW - Promoter Regions, Genetic KW - genetics KW - Protein Isoforms KW - Protein Structure, Tertiary KW - RNA, Neoplasm KW - Recombinant Fusion Proteins KW - physiology KW - Thalidomide KW - analogs & derivatives KW - Up-Regulation KW - Xenograft Model Antitumor Assays N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S UR - https://doi.org/10.1182/blood-2012-05-428573 ER -