TY - GEN AU - Lima,Raquel T AU - Barron,Gemma A AU - Grabowska,Joanna A AU - Bermano,Giovanna AU - Kaur,Simranjeet AU - Roy,Nilanjan AU - Vasconcelos,M Helena AU - Lin,Paul K T TI - Cytotoxicity and cell death mechanisms induced by a novel bisnaphthalimidopropyl derivative against the NCI-H460 non-small lung cancer cell line SN - 1875-5992 PY - 2013///0805 KW - Acetylation KW - Antineoplastic Agents KW - chemical synthesis KW - Apoptosis KW - drug effects KW - Biogenic Polyamines KW - Caspase 3 KW - genetics KW - Cell Cycle KW - Cell Line, Tumor KW - Cyclohexylamines KW - Dose-Response Relationship, Drug KW - Gene Expression Regulation, Neoplastic KW - Humans KW - Molecular Docking Simulation KW - Naphthalimides KW - Poly(ADP-ribose) Polymerase Inhibitors KW - Poly(ADP-ribose) Polymerases KW - Quinolones KW - Signal Transduction KW - Sirtuin 1 KW - antagonists & inhibitors KW - Sirtuin 2 KW - Structure-Activity Relationship KW - Tubulin N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.2174/1871520611313030005 ER -