Watanabe, Teppei <br/><br/>
Inhibition of transforming growth factor β1/Smad3 signaling decreases hypoxia-inducible factor-1α protein stability by inducing prolyl hydroxylase 2 expression in human periodontal ligament cells.  [electronic resource] 

 -  Journal of periodontology  Sep 2013 
 - 1346-52 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1943-3670 
<br/><br/><label>Standard No.: </label>10.1902/jop.2012.120373  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Adolescent<br/>Cell Culture Techniques<br/>Cells, Cultured<br/>Chronic Periodontitis--metabolism<br/>Cycloheximide--pharmacology<br/>Dose-Response Relationship, Drug<br/>Fibroblasts--drug effects<br/>Humans<br/>Hypoxia-Inducible Factor 1, alpha Subunit--antagonists & inhibitors<br/>Hypoxia-Inducible Factor-Proline Dioxygenases--drug effects<br/>Isoquinolines--pharmacology<br/>Male<br/>Periodontal Ligament--cytology<br/>Phosphorylation<br/>Protein Synthesis Inhibitors--pharmacology<br/>Pyridines--pharmacology<br/>Pyrroles--pharmacology<br/>Signal Transduction--drug effects<br/>Smad3 Protein--antagonists & inhibitors<br/>Time Factors<br/>Transforming Growth Factor beta1--antagonists & inhibitors