Angelini, Alessandro

Bicyclization and tethering to albumin yields long-acting peptide antagonists. [electronic resource] - Journal of medicinal chemistry Nov 2012 - 10187-97 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1520-4804

10.1021/jm301276e doi


Animals
Bridged Bicyclo Compounds--blood
Cyclization
Female
Mice
Mice, Inbred BALB C
Models, Molecular
Molecular Structure
Peptides, Cyclic--blood
Serum Albumin--metabolism
Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
Structure-Activity Relationship
Urokinase-Type Plasminogen Activator--antagonists & inhibitors