Poly(ADP-ribose) polymerase 1 inhibition protects against low shear stress induced inflammation. [electronic resource]
- Biochimica et biophysica acta Jan 2013
- 59-68 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0006-3002
10.1016/j.bbamcr.2012.10.013 doi
Cells, Cultured Cytoprotection--drug effects Enzyme Inhibitors--pharmacology Gene Expression Regulation, Enzymologic--drug effects Human Umbilical Vein Endothelial Cells--drug effects Humans Inflammation--etiology Inflammation Mediators--metabolism Nitric Oxide Synthase Type II--genetics Poly (ADP-Ribose) Polymerase-1 Poly(ADP-ribose) Polymerase Inhibitors Poly(ADP-ribose) Polymerases--genetics RNA, Small Interfering--pharmacology Shear Strength--drug effects Signal Transduction--drug effects Stress, Mechanical Time Factors