TY  - GEN
AU  - Tsubaki,Masanobu
AU  - Itoh,Tatsuki
AU  - Satou,Takao
AU  - Imano,Motohiro
AU  - Komai,Makiko
AU  - Ogawa,Naoki
AU  - Mukai,Junji
AU  - Nishida,Shozo
TI  - Nitrogen-containing bisphosphonates induce apoptosis of hematopoietic tumor cells via inhibition of Ras signaling pathways and Bim-mediated activation of the intrinsic apoptotic pathway
SN  - 1873-2968
PY  - 2013///0225
KW  - Alendronate
KW  - adverse effects
KW  - Antineoplastic Agents
KW  - Apoptosis
KW  - drug effects
KW  - Apoptosis Regulatory Proteins
KW  - antagonists & inhibitors
KW  - Bcl-2-Like Protein 11
KW  - Bone Density Conservation Agents
KW  - Cell Line, Tumor
KW  - Cell Nucleus
KW  - Cell Survival
KW  - Diphosphonates
KW  - Gene Expression Regulation, Neoplastic
KW  - Gene Silencing
KW  - Hematologic Neoplasms
KW  - drug therapy
KW  - Humans
KW  - Imidazoles
KW  - MAP Kinase Signaling System
KW  - Membrane Proteins
KW  - Neoplasm Proteins
KW  - Protein Kinase Inhibitors
KW  - pharmacology
KW  - Protein Prenylation
KW  - Proto-Oncogene Proteins
KW  - Proto-Oncogene Proteins p21(ras)
KW  - Signal Transduction
KW  - TOR Serine-Threonine Kinases
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1016/j.bcp.2012.10.009
ER  -