TY  - GEN
AU  - Witte,Maarten E
AU  - Nijland,Philip G
AU  - Drexhage,Joost A R
AU  - Gerritsen,Wouter
AU  - Geerts,Dirk
AU  - van Het Hof,Bert
AU  - Reijerkerk,Arie
AU  - de Vries,Helga E
AU  - van der Valk,Paul
AU  - van Horssen,Jack
TI  - Reduced expression of PGC-1α partly underlies mitochondrial changes and correlates with neuronal loss in multiple sclerosis cortex
SN  - 1432-0533
PY  - 2013///0625
KW  - Adult
KW  - Aged
KW  - Aged, 80 and over
KW  - Blotting, Western
KW  - Cell Count
KW  - Cerebral Cortex
KW  - pathology
KW  - Down-Regulation
KW  - Female
KW  - Genetic Vectors
KW  - Gyrus Cinguli
KW  - Heat-Shock Proteins
KW  - biosynthesis
KW  - Humans
KW  - Immunohistochemistry
KW  - Lentivirus
KW  - genetics
KW  - Male
KW  - Middle Aged
KW  - Mitochondria
KW  - Multiple Sclerosis
KW  - Neurons
KW  - Oxidation-Reduction
KW  - Oxidative Phosphorylation
KW  - Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha
KW  - Pyramidal Cells
KW  - RNA, Small Interfering
KW  - Reactive Oxygen Species
KW  - metabolism
KW  - Real-Time Polymerase Chain Reaction
KW  - Tissue Banks
KW  - Transcription Factors
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1007/s00401-012-1052-y
ER  -