TY - GEN AU - Contini,Alessandro AU - Cappelletti,Graziella AU - Cartelli,Daniele AU - Fontana,Gabriele AU - Gelmi,Maria Luisa TI - Molecular dynamics and tubulin polymerization kinetics study on 1,14-heterofused taxanes: evidence of stabilization of the tubulin head-to-tail dimer-dimer interaction SN - 1742-2051 PY - 2013///0502 KW - Bridged-Ring Compounds KW - metabolism KW - Cell Line, Tumor KW - Computational Biology KW - Humans KW - Kinetics KW - MCF-7 Cells KW - Microtubules KW - chemistry KW - Models, Molecular KW - Molecular Dynamics Simulation KW - Paclitaxel KW - analogs & derivatives KW - Protein Binding KW - Protein Conformation KW - Protein Multimerization KW - Taxoids KW - Tubulin N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1039/c2mb25326g ER -