TY  - GEN
AU  - Nakagawa,T
AU  - Nagayasu,K
AU  - Nishitani,N
AU  - Shirakawa,H
AU  - Sekiguchi,K
AU  - Ikarashi,Y
AU  - Kase,Y
AU  - Kaneko,S
TI  - Yokukansan inhibits morphine tolerance and physical dependence in mice: the role of α₂A-adrenoceptor
SN  - 1873-7544
PY  - 2013///0509
KW  - Adrenergic Agents
KW  - pharmacology
KW  - Adrenergic alpha-Antagonists
KW  - pharmacokinetics
KW  - Adrenergic beta-Antagonists
KW  - Analysis of Variance
KW  - Animals
KW  - Behavior, Addictive
KW  - drug therapy
KW  - Disease Models, Animal
KW  - Dose-Response Relationship, Drug
KW  - Drug Tolerance
KW  - Drugs, Chinese Herbal
KW  - therapeutic use
KW  - Guanosine 5'-O-(3-Thiotriphosphate)
KW  - Guanosine Diphosphate
KW  - Isotopes
KW  - Male
KW  - Mice
KW  - Morphine Dependence
KW  - Norepinephrine Plasma Membrane Transport Proteins
KW  - metabolism
KW  - Pain Threshold
KW  - drug effects
KW  - Propranolol
KW  - Protein Binding
KW  - Radioligand Assay
KW  - Receptors, Adrenergic, alpha-2
KW  - Time Factors
KW  - Tropanes
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1016/j.neuroscience.2012.09.079
ER  -