Limited phenotypic effects of selectively augmenting the SMN protein in the neurons of a mouse model of severe spinal muscular atrophy. [electronic resource]
- PloS one 2012
- e46353 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
1932-6203
10.1371/journal.pone.0046353 doi
Animals Cellular Microenvironment Disease Models, Animal Female Genetic Therapy Humans Male Mice Mice, Transgenic Motor Activity Motor Neurons--metabolism Muscular Atrophy, Spinal--genetics Neuromuscular Junction--genetics Organ Specificity Phenotype Severity of Illness Index Survival Rate Survival of Motor Neuron 1 Protein--genetics Synapses--genetics Transgenes