van der Vries, Erhard <br/><br/>
H1N1 2009 pandemic influenza virus: resistance of the I223R neuraminidase mutant explained by kinetic and structural analysis.  [electronic resource] 

 -  PLoS pathogens  Sep 2012 
 - e1002914 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1553-7374 
<br/><br/><label>Standard No.: </label>10.1371/journal.ppat.1002914  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Adamantane--pharmacology<br/>Amino Acid Substitution<br/>Antiviral Agents--pharmacology<br/>Binding Sites--genetics<br/>Crystallography, X-Ray<br/>Drug Resistance, Viral--genetics<br/>Enzyme Inhibitors--pharmacology<br/>Humans<br/>Hydrophobic and Hydrophilic Interactions<br/>Influenza A Virus, H1N1 Subtype--drug effects<br/>Influenza, Human--drug therapy<br/>Mutation<br/>Neuraminidase--antagonists & inhibitors<br/>Oseltamivir--pharmacology<br/>Pandemics<br/>Protein Conformation<br/>Zanamivir--pharmacology