TY - GEN AU - Tibes,Raoul AU - Bogenberger,James M AU - Benson,Kasey L AU - Mesa,Ruben A TI - Current outlook on molecular pathogenesis and treatment of myeloproliferative neoplasms SN - 1179-2000 PY - 2013///0328 KW - Adaptor Proteins, Signal Transducing KW - Alleles KW - Benzamides KW - therapeutic use KW - Bridged-Ring Compounds KW - Carbazoles KW - Chromatin KW - genetics KW - DNA (Cytosine-5-)-Methyltransferases KW - DNA Methyltransferase 3A KW - DNA-Binding Proteins KW - Dioxygenases KW - Enhancer of Zeste Homolog 2 Protein KW - Epigenesis, Genetic KW - Furans KW - Gene Expression Regulation KW - Humans KW - Ikaros Transcription Factor KW - Intracellular Signaling Peptides and Proteins KW - Isocitrate Dehydrogenase KW - Janus Kinase 2 KW - antagonists & inhibitors KW - Mutation KW - Myeloproliferative Disorders KW - Nitriles KW - Polycomb Repressive Complex 2 KW - Proteins KW - Proto-Oncogene Proteins KW - Proto-Oncogene Proteins c-cbl KW - Pyrazoles KW - Pyrimidines KW - Pyrrolidines KW - Receptors, Thrombopoietin KW - Repressor Proteins KW - Signal Transduction KW - Spliceosomes KW - metabolism KW - Sulfonamides N1 - Publication Type: Journal Article; Review UR - https://doi.org/10.1007/s40291-012-0006-3 ER -