TY - GEN AU - Winter,Georg E AU - Rix,Uwe AU - Carlson,Scott M AU - Gleixner,Karoline V AU - Grebien,Florian AU - Gridling,Manuela AU - Müller,André C AU - Breitwieser,Florian P AU - Bilban,Martin AU - Colinge,Jacques AU - Valent,Peter AU - Bennett,Keiryn L AU - White,Forest M AU - Superti-Furga,Giulio TI - Systems-pharmacology dissection of a drug synergy in imatinib-resistant CML SN - 1552-4469 PY - 2013///0212 KW - Aniline Compounds KW - pharmacology KW - Animals KW - Antineoplastic Combined Chemotherapy Protocols KW - Apoptosis KW - drug effects KW - Benzamides KW - Cell Line, Tumor KW - Cell Survival KW - Dose-Response Relationship, Drug KW - Down-Regulation KW - Drug Resistance, Neoplasm KW - Drug Synergism KW - Fusion Proteins, bcr-abl KW - antagonists & inhibitors KW - Imatinib Mesylate KW - Leukemia, Myelogenous, Chronic, BCR-ABL Positive KW - drug therapy KW - Mice KW - Nitriles KW - Piperazines KW - Protein Kinase Inhibitors KW - Proteomics KW - Proto-Oncogene Proteins c-myc KW - Pyrazoles KW - Pyrimidines KW - Quinolines KW - Structure-Activity Relationship KW - Systems Biology N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1038/nchembio.1085 ER -