TY - GEN AU - Yoshimoto,Maisa AU - Ding,Keyue AU - Sweet,Joan M AU - Ludkovski,Olga AU - Trottier,Greg AU - Song,Kyu S AU - Joshua,Anthony M AU - Fleshner,Neil E AU - Squire,Jeremy A AU - Evans,Andrew J TI - PTEN losses exhibit heterogeneity in multifocal prostatic adenocarcinoma and are associated with higher Gleason grade SN - 1530-0285 PY - 2013///0821 KW - Adenocarcinoma KW - enzymology KW - Adult KW - Aged KW - Biomarkers, Tumor KW - analysis KW - Biopsy, Large-Core Needle KW - Chi-Square Distribution KW - Down-Regulation KW - Genetic Predisposition to Disease KW - Humans KW - In Situ Hybridization, Fluorescence KW - Male KW - Middle Aged KW - Neoplasm Grading KW - Neoplasms, Multiple Primary KW - Oncogene Proteins, Fusion KW - genetics KW - PTEN Phosphohydrolase KW - Phenotype KW - Prostatectomy KW - Prostatic Neoplasms KW - Tissue Array Analysis KW - Treatment Outcome N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1038/modpathol.2012.162 ER -