Helsby, N A <br/><br/>
In vitro metabolism of the biguanide antimalarials in human liver microsomes: evidence for a role of the mephenytoin hydroxylase (P450 MP) enzyme.  [electronic resource] 

 -  British journal of clinical pharmacology  Aug 1990 
 - 287-91 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>0306-5251 
<br/><br/><label>Standard No.: </label>10.1111/j.1365-2125.1990.tb03777.x  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Antimalarials--pharmacokinetics<br/>Aryl Hydrocarbon Hydroxylases<br/>Biotransformation<br/>Cytochrome P-450 CYP2C19<br/>Cytochrome P-450 Enzyme System--metabolism<br/>Humans<br/>In Vitro Techniques<br/>Mephenytoin--pharmacology<br/>Microsomes, Liver--enzymology<br/>Mixed Function Oxygenases--metabolism<br/>Proguanil--analogs & derivatives<br/>Sparteine--pharmacology<br/>Tolbutamide--pharmacology