TY  - GEN
AU  - Kung,Charles
AU  - Hixon,Jeff
AU  - Choe,Sung
AU  - Marks,Kevin
AU  - Gross,Stefan
AU  - Murphy,Erin
AU  - DeLaBarre,Byron
AU  - Cianchetta,Giovanni
AU  - Sethumadhavan,Shalini
AU  - Wang,Xiling
AU  - Yan,Shunqi
AU  - Gao,Yi
AU  - Fang,Cheng
AU  - Wei,Wentao
AU  - Jiang,Fan
AU  - Wang,Shaohui
AU  - Qian,Kevin
AU  - Saunders,Jeff
AU  - Driggers,Ed
AU  - Woo,Hin Koon
AU  - Kunii,Kaiko
AU  - Murray,Stuart
AU  - Yang,Hua
AU  - Yen,Katharine
AU  - Liu,Wei
AU  - Cantley,Lewis C
AU  - Vander Heiden,Matthew G
AU  - Su,Shinsan M
AU  - Jin,Shengfang
AU  - Salituro,Francesco G
AU  - Dang,Lenny
TI  - Small molecule activation of PKM2 in cancer cells induces serine auxotrophy
SN  - 1879-1301
PY  - 2014///0710
KW  - Allosteric Site
KW  - drug effects
KW  - Carrier Proteins
KW  - metabolism
KW  - Cell Proliferation
KW  - Dose-Response Relationship, Drug
KW  - Humans
KW  - Membrane Proteins
KW  - Models, Molecular
KW  - Molecular Structure
KW  - Serine
KW  - Small Molecule Libraries
KW  - chemical synthesis
KW  - Structure-Activity Relationship
KW  - Thyroid Hormones
KW  - Tumor Cells, Cultured
KW  - Thyroid Hormone-Binding Proteins
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1016/j.chembiol.2012.07.021
ER  -