The role of eight polymorphisms in three candidate genes in determining the susceptibility, phenotype, and response to anti-TNF therapy in patients with rheumatoid arthritis. [electronic resource]
- Clinical and experimental rheumatology
- 939-42 p. digital
Publication Type: Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
0392-856X
Adolescent Adult Aged Aged, 80 and over Antirheumatic Agents--pharmacology Arthritis, Rheumatoid--diagnosis Autoantibodies--blood Biomarkers--blood Case-Control Studies Chi-Square Distribution Female Genetic Predisposition to Disease HLA-DRB1 Chains--genetics Humans Hydrolases--genetics Italy--epidemiology Linear Models Male Middle Aged Multivariate Analysis Odds Ratio Osteopontin--genetics Peptides, Cyclic--immunology Perforin Phenotype Polymorphism, Single Nucleotide Pore Forming Cytotoxic Proteins--genetics Protein-Arginine Deiminase Type 4 Protein-Arginine Deiminases Rheumatoid Factor--blood Time Factors Treatment Outcome Tumor Necrosis Factor-alpha--antagonists & inhibitors White People--genetics Young Adult