Sharp, Swee Y <br/><br/>
Co-crystalization and in vitro biological characterization of 5-aryl-4-(5-substituted-2-4-dihydroxyphenyl)-1,2,3-thiadiazole Hsp90 inhibitors.  [electronic resource] 

 -  PloS one  2012 
 - e44642 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1932-6203 
<br/><br/><label>Standard No.: </label>10.1371/journal.pone.0044642  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Antineoplastic Agents--pharmacology<br/>Apoptosis<br/>Biomarkers, Tumor--metabolism<br/>Cell Line, Tumor<br/>Crystallization<br/>Crystallography, X-Ray--methods<br/>Drug Screening Assays, Antitumor<br/>HSP27 Heat-Shock Proteins--chemistry<br/>HSP72 Heat-Shock Proteins--chemistry<br/>HSP90 Heat-Shock Proteins--antagonists & inhibitors<br/>Humans<br/>In Vitro Techniques<br/>Inhibitory Concentration 50<br/>Models, Chemical<br/>Mutation<br/>Protein Binding<br/>Protein Structure, Tertiary<br/>Recombinant Proteins--chemistry<br/>Thiadiazoles--chemistry