Lu, Yue

Saucerneol D inhibits eicosanoid generation and degranulation through suppression of Syk kinase in mast cells. [electronic resource] - Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association Dec 2012 - 4382-8 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1873-6351

10.1016/j.fct.2012.08.053 doi


Animals
Arachidonate 5-Lipoxygenase--genetics
Bone Marrow Cells--cytology
Cell Degranulation--drug effects
Cyclooxygenase 2--genetics
Eicosanoids--antagonists & inhibitors
Intracellular Signaling Peptides and Proteins--genetics
Leukotriene C4--genetics
Lignans--pharmacology
MAP Kinase Signaling System
Male
Mast Cells--drug effects
Mice
Mice, Inbred BALB C
Mitogen-Activated Protein Kinase 3--metabolism
Mitogen-Activated Protein Kinases--metabolism
NF-kappa B--metabolism
Phospholipase C gamma--genetics
Phosphorylation
Plant Extracts--pharmacology
Protein-Tyrosine Kinases--genetics
Saururaceae--chemistry
Syk Kinase