Maria, Durvanei Augusto <br/><br/>
A novel proteasome inhibitor acting in mitochondrial dysfunction, ER stress and ROS production.  [electronic resource] 

 -  Investigational new drugs  Jun 2013 
 - 493-505 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1573-0646 
<br/><br/><label>Standard No.: </label>10.1007/s10637-012-9871-1  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Antineoplastic Agents--pharmacology<br/>Apoptosis--drug effects<br/>Arthropod Proteins<br/>Calcium--metabolism<br/>Caspase 3--metabolism<br/>Cell Line, Tumor<br/>Endoplasmic Reticulum Chaperone BiP<br/>Endoplasmic Reticulum Stress--drug effects<br/>Factor Xa Inhibitors<br/>Heat-Shock Proteins--metabolism<br/>Hydrogen Peroxide--metabolism<br/>Membrane Potential, Mitochondrial--drug effects<br/>Mice<br/>Mitochondria--drug effects<br/>NIH 3T3 Cells<br/>Nitric Oxide--metabolism<br/>Proteasome Inhibitors--pharmacology<br/>Recombinant Proteins--pharmacology<br/>Salivary Proteins and Peptides--pharmacology<br/>Transcription Factor CHOP--metabolism