TY - GEN AU - Domingo-Domenech,Josep AU - Vidal,Samuel J AU - Rodriguez-Bravo,Veronica AU - Castillo-Martin,Mireia AU - Quinn,S Aidan AU - Rodriguez-Barrueco,Ruth AU - Bonal,Dennis M AU - Charytonowicz,Elizabeth AU - Gladoun,Nataliya AU - de la Iglesia-Vicente,Janis AU - Petrylak,Daniel P AU - Benson,Mitchell C AU - Silva,Jose M AU - Cordon-Cardo,Carlos TI - Suppression of acquired docetaxel resistance in prostate cancer through depletion of notch- and hedgehog-dependent tumor-initiating cells SN - 1878-3686 PY - 2012///1126 KW - Animals KW - Apoptosis KW - Cell Line, Tumor KW - Disease Progression KW - Docetaxel KW - Drug Resistance, Neoplasm KW - Hedgehog Proteins KW - genetics KW - Humans KW - Male KW - Mice KW - Mice, Inbred NOD KW - Mice, SCID KW - Molecular Sequence Data KW - Neoplastic Stem Cells KW - metabolism KW - Prostatic Neoplasms KW - drug therapy KW - Proto-Oncogene Proteins c-akt KW - antagonists & inhibitors KW - Proto-Oncogene Proteins c-bcl-2 KW - Receptors, Notch KW - Signal Transduction KW - Taxoids KW - pharmacology KW - Xenograft Model Antitumor Assays N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1016/j.ccr.2012.07.016 ER -