TY  - GEN
AU  - Fuchs,Ines
AU  - Hafner-Blumenstiel,Verena
AU  - Markert,Christoph
AU  - Burhenne,Jürgen
AU  - Weiss,Johanna
AU  - Haefeli,Walter Emil
AU  - Mikus,Gerd
TI  - Effect of the CYP3A inhibitor ketoconazole on the PXR-mediated induction of CYP3A activity
SN  - 1432-1041
PY  - 2013///0801
KW  - Adult
KW  - Area Under Curve
KW  - Biotransformation
KW  - Cross-Over Studies
KW  - Cytochrome P-450 CYP3A
KW  - biosynthesis
KW  - Cytochrome P-450 CYP3A Inhibitors
KW  - Drug Administration Schedule
KW  - Drug Interactions
KW  - Enzyme Induction
KW  - Enzyme Inhibitors
KW  - administration & dosage
KW  - Germany
KW  - Humans
KW  - Hydroxylation
KW  - Hypericum
KW  - Ketoconazole
KW  - Male
KW  - Metabolic Clearance Rate
KW  - Midazolam
KW  - Middle Aged
KW  - Plant Extracts
KW  - Plants, Medicinal
KW  - Pregnane X Receptor
KW  - Receptors, Steroid
KW  - drug effects
KW  - Substrate Specificity
KW  - Transcription, Genetic
KW  - Young Adult
N1  - Publication Type: Comparative Study; Journal Article; Randomized Controlled Trial
UR  - https://doi.org/10.1007/s00228-012-1388-1
ER  -