TY - GEN AU - Vélez de Mendizábal,Nieves AU - Vásquez-Bahena,Dalia AU - Jiménez-Andrade,Juan M AU - Ortiz,Mario I AU - Castañeda-Hernández,Gilberto AU - Trocóniz,Iñaki F TI - Semi-mechanistic modeling of the interaction between the central and peripheral effects in the antinociceptive response to lumiracoxib in rats SN - 1550-7416 PY - 2013///0404 KW - Animals KW - Cyclooxygenase 2 KW - drug effects KW - Cyclooxygenase 2 Inhibitors KW - administration & dosage KW - Diclofenac KW - Disease Models, Animal KW - Female KW - Formaldehyde KW - Injections KW - Injections, Spinal KW - Models, Biological KW - Nonlinear Dynamics KW - Pain KW - drug therapy KW - Pain Measurement KW - Rats KW - Rats, Wistar KW - Time Factors KW - Up-Regulation N1 - Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1208/s12248-012-9405-y ER -