TY - GEN AU - Hoff,Paulo M AU - Hochhaus,Andreas AU - Pestalozzi,Bernhard C AU - Tebbutt,Niall C AU - Li,Jin AU - Kim,Tae Won AU - Koynov,Krassimir D AU - Kurteva,Galina AU - Pintér,Tamás AU - Cheng,Ying AU - van Eyll,Brigitte AU - Pike,Laura AU - Fielding,Anitra AU - Robertson,Jane D AU - Saunders,Mark P TI - Cediranib plus FOLFOX/CAPOX versus placebo plus FOLFOX/CAPOX in patients with previously untreated metastatic colorectal cancer: a randomized, double-blind, phase III study (HORIZON II) SN - 1527-7755 PY - 2012///1219 KW - Administration, Oral KW - Adult KW - Aged KW - Aged, 80 and over KW - Antineoplastic Combined Chemotherapy Protocols KW - therapeutic use KW - Brazil KW - Capecitabine KW - Colorectal Neoplasms KW - drug therapy KW - Deoxycytidine KW - analogs & derivatives KW - Disease-Free Survival KW - Dose-Response Relationship, Drug KW - Double-Blind Method KW - Drug Administration Schedule KW - Female KW - Fluorouracil KW - Humans KW - Infusions, Intravenous KW - Kaplan-Meier Estimate KW - Leucovorin KW - Male KW - Middle Aged KW - Neoplasm Invasiveness KW - pathology KW - Neoplasm Metastasis KW - Neoplasm Staging KW - Organoplatinum Compounds KW - Prognosis KW - Proportional Hazards Models KW - Pyridines KW - Quinazolines KW - Survival Analysis N1 - Publication Type: Clinical Trial, Phase III; Comparative Study; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1200/JCO.2012.42.6031 ER -