Roller, Devin G

Synthetic lethal screening with small-molecule inhibitors provides a pathway to rational combination therapies for melanoma. [electronic resource] - Molecular cancer therapeutics Nov 2012 - 2505-15 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1538-8514

10.1158/1535-7163.MCT-12-0461 doi


Antineoplastic Agents--analysis
Antineoplastic Combined Chemotherapy Protocols--pharmacology
Cell Death--drug effects
Cell Line, Tumor
Diclofenac--pharmacology
Drug Synergism
Extracellular Signal-Regulated MAP Kinases--antagonists & inhibitors
Gene Expression Regulation, Neoplastic--drug effects
Genome, Human--genetics
Humans
Melanoma--drug therapy
Niacinamide--analogs & derivatives
Phenylurea Compounds--pharmacology
Phospholipases A2, Cytosolic--metabolism
Signal Transduction--drug effects
Skin Neoplasms--drug therapy
Small Molecule Libraries--analysis
Sorafenib