Genistein demethylates the promoter of CHD5 and inhibits neuroblastoma growth in vivo. [electronic resource]
- International journal of molecular medicine Nov 2012
- 1081-6 p. digital
Publication Type: Journal Article
1791-244X
10.3892/ijmm.2012.1118 doi
Animals Antineoplastic Agents, Phytogenic--pharmacology Base Sequence Cell Line, Tumor Cell Proliferation--drug effects CpG Islands DNA (Cytosine-5-)-Methyltransferases--genetics DNA Helicases--genetics DNA Methylation Gene Expression--drug effects Gene Expression Regulation, Neoplastic--drug effects Genistein--pharmacology Humans Mice Mice, Inbred BALB C Mice, Nude Microvessels--pathology Molecular Sequence Data Neovascularization, Pathologic Nerve Tissue Proteins--genetics Neuroblastoma--blood supply Promoter Regions, Genetic Protein Isoforms--genetics Sequence Analysis, DNA Tumor Burden--drug effects Xenograft Model Antitumor Assays DNA Methyltransferase 3B