TY  - GEN
AU  - Iglesias-Bartolome,Ramiro
AU  - Patel,Vyomesh
AU  - Cotrim,Ana
AU  - Leelahavanichkul,Kantima
AU  - Molinolo,Alfredo A
AU  - Mitchell,James B
AU  - Gutkind,J Silvio
TI  - mTOR inhibition prevents epithelial stem cell senescence and protects from radiation-induced mucositis
SN  - 1875-9777
PY  - 2013///0529
KW  - Animals
KW  - Carcinoma, Squamous Cell
KW  - enzymology
KW  - Cell Compartmentation
KW  - drug effects
KW  - Cell Death
KW  - Cell Proliferation
KW  - Cells, Cultured
KW  - Cellular Senescence
KW  - Clone Cells
KW  - Cytoprotection
KW  - Epithelial Cells
KW  - Head and Neck Neoplasms
KW  - Humans
KW  - Keratinocytes
KW  - Mice
KW  - Mouth Mucosa
KW  - Mucositis
KW  - Oxidative Stress
KW  - Radiation Injuries
KW  - Radiation, Ionizing
KW  - Sirolimus
KW  - pharmacology
KW  - Stem Cells
KW  - Superoxide Dismutase
KW  - metabolism
KW  - TOR Serine-Threonine Kinases
KW  - antagonists & inhibitors
N1  - Publication Type: Journal Article; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1016/j.stem.2012.06.007
ER  -