TY - GEN AU - Petrasek,Jan AU - Bala,Shashi AU - Csak,Timea AU - Lippai,Dora AU - Kodys,Karen AU - Menashy,Victoria AU - Barrieau,Matthew AU - Min,So-Yun AU - Kurt-Jones,Evelyn A AU - Szabo,Gyongyi TI - IL-1 receptor antagonist ameliorates inflammasome-dependent alcoholic steatohepatitis in mice SN - 1558-8238 PY - 2013///0201 KW - Animals KW - Carrier Proteins KW - biosynthesis KW - Caspase 1 KW - physiology KW - Chemokine CCL2 KW - Drug Evaluation, Preclinical KW - Ethanol KW - toxicity KW - Fatty Liver, Alcoholic KW - drug therapy KW - Female KW - Hepatocytes KW - metabolism KW - Inflammasomes KW - Interleukin 1 Receptor Antagonist Protein KW - therapeutic use KW - Interleukin-1alpha KW - Interleukin-1beta KW - Kupffer Cells KW - pathology KW - Liver Cirrhosis KW - etiology KW - Mice KW - Mice, Inbred C57BL KW - Mice, Knockout KW - NLR Family, Pyrin Domain-Containing 3 Protein KW - Receptors, Interleukin-1 Type I KW - deficiency KW - Recombinant Proteins KW - Signal Transduction KW - drug effects KW - Toll-Like Receptor 4 KW - Up-Regulation N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Review UR - https://doi.org/10.1172/JCI60777 ER -