Petrasek, Jan <br/><br/>
IL-1 receptor antagonist ameliorates inflammasome-dependent alcoholic steatohepatitis in mice.  [electronic resource] 

 -  The Journal of clinical investigation  Oct 2012 
 - 3476-89 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, N.I.H., Extramural; Review 
<br/><br/><label>ISSN: </label>1558-8238 
<br/><br/><label>Standard No.: </label>10.1172/JCI60777  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Carrier Proteins--biosynthesis<br/>Caspase 1--physiology<br/>Chemokine CCL2--biosynthesis<br/>Drug Evaluation, Preclinical<br/>Ethanol--toxicity<br/>Fatty Liver, Alcoholic--drug therapy<br/>Female<br/>Hepatocytes--metabolism<br/>Inflammasomes--physiology<br/>Interleukin 1 Receptor Antagonist Protein--therapeutic use<br/>Interleukin-1alpha--biosynthesis<br/>Interleukin-1beta--biosynthesis<br/>Kupffer Cells--pathology<br/>Liver Cirrhosis--etiology<br/>Mice<br/>Mice, Inbred C57BL<br/>Mice, Knockout<br/>NLR Family, Pyrin Domain-Containing 3 Protein<br/>Receptors, Interleukin-1 Type I--deficiency<br/>Recombinant Proteins--therapeutic use<br/>Signal Transduction--drug effects<br/>Toll-Like Receptor 4--physiology<br/>Up-Regulation--drug effects