Muller, Patrick Y <br/><br/>
The determination and interpretation of the therapeutic index in drug development.  [electronic resource] 

 -  Nature reviews. Drug discovery  Oct 2012 
 - 751-61 p.  digital 
<br/><br/> Publication Type: Journal Article; Review 
<br/><br/><label>ISSN: </label>1474-1784 
<br/><br/><label>Standard No.: </label>10.1038/nrd3801  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Biomarkers, Pharmacological--metabolism<br/>Drug Discovery--trends<br/>Drug-Related Side Effects and Adverse Reactions<br/>Humans<br/>Pharmaceutical Preparations--administration & dosage<br/>Treatment Outcome