TY - GEN AU - Strouse,J Jacob AU - Ivnitski-Steele,Irena AU - Khawaja,Hadya M AU - Perez,Dominique AU - Ricci,Jerec AU - Yao,Tuanli AU - Weiner,Warren S AU - Schroeder,Chad E AU - Simpson,Denise S AU - Maki,Brooks E AU - Li,Kelin AU - Golden,Jennifer E AU - Foutz,Terry D AU - Waller,Anna AU - Evangelisti,Annette M AU - Young,Susan M AU - Chavez,Stephanie E AU - Garcia,Matthew J AU - Ursu,Oleg AU - Bologa,Cristian G AU - Carter,Mark B AU - Salas,Virginia M AU - Gouveia,Kristine AU - Tegos,George P AU - Oprea,Tudor I AU - Edwards,Bruce S AU - Aubé,Jeffrey AU - Larson,Richard S AU - Sklar,Larry A TI - A selective ATP-binding cassette subfamily G member 2 efflux inhibitor revealed via high-throughput flow cytometry SN - 1552-454X PY - 2013///0604 KW - ATP Binding Cassette Transporter, Subfamily B KW - ATP Binding Cassette Transporter, Subfamily B, Member 1 KW - antagonists & inhibitors KW - ATP Binding Cassette Transporter, Subfamily G, Member 2 KW - ATP-Binding Cassette Transporters KW - Animals KW - Antineoplastic Agents KW - pharmacology KW - Cell Line KW - Drug Resistance, Neoplasm KW - Flow Cytometry KW - High-Throughput Screening Assays KW - Humans KW - Inhibitory Concentration 50 KW - Mice KW - Mice, SCID KW - Neoplasm Proteins KW - Pyrazoles KW - Pyrimidines KW - Small Molecule Libraries KW - Structure-Activity Relationship KW - Tumor Burden KW - drug effects KW - Xenograft Model Antitumor Assays N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1177/1087057112456875 ER -