Yang, Dongmei

RGS2 overexpression or G(i) inhibition rescues the impaired PKA signaling and slow AP firing of cultured adult rabbit pacemaker cells. [electronic resource] - Journal of molecular and cellular cardiology Nov 2012 - 687-94 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Intramural

1095-8584

10.1016/j.yjmcc.2012.08.007 doi


Action Potentials
Adenoviridae--genetics
Adrenergic beta-Agonists--pharmacology
Animals
Calcium-Binding Proteins--metabolism
Cell Shape
Cells, Cultured
Cyclic AMP
Cyclic AMP-Dependent Protein Kinases--antagonists & inhibitors
GTP-Binding Protein alpha Subunits, Gi-Go--metabolism
Genetic Vectors
Isoproterenol--pharmacology
Pertussis Toxin--pharmacology
Phosphorylation
Protein Kinase Inhibitors--pharmacology
Protein Processing, Post-Translational
RGS Proteins--genetics
Rabbits
Recombinant Proteins--genetics
Ryanodine Receptor Calcium Release Channel--metabolism
Second Messenger Systems
Sinoatrial Node--cytology
Transfection