Curcumin suppresses the TPA-induced invasion through inhibition of PKCα-dependent MMP-expression in MCF-7 human breast cancer cells. [electronic resource]
- Phytomedicine : international journal of phytotherapy and phytopharmacology Sep 2012
- 1085-92 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1618-095X
10.1016/j.phymed.2012.07.002 doi
Antineoplastic Agents, Phytogenic--pharmacology Biological Transport--drug effects Breast Neoplasms--drug therapy Cell Movement--drug effects Curcuma--chemistry Curcumin--pharmacology Female Humans JNK Mitogen-Activated Protein Kinases--metabolism MCF-7 Cells Matrix Metalloproteinase 9--metabolism NF-kappa B--metabolism Neoplasm Metastasis--prevention & control Phytotherapy Plant Extracts--pharmacology Protein Kinase C-alpha--metabolism Signal Transduction Tetradecanoylphorbol Acetate Transcription Factor AP-1--metabolism p38 Mitogen-Activated Protein Kinases--metabolism