Scheer, Nico

Generation and characterization of novel cytochrome P450 Cyp2c gene cluster knockout and CYP2C9 humanized mouse lines. [electronic resource] - Molecular pharmacology Dec 2012 - 1022-9 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1521-0111

10.1124/mol.112.080036 doi


Animals
Aryl Hydrocarbon Hydroxylases--genetics
Cytochrome P-450 CYP2C9
Cytochrome P-450 Enzyme Inhibitors
Cytochrome P-450 Enzyme System--genetics
Humans
Hydroxylation
Inactivation, Metabolic
Liver--drug effects
Mice
Mice, Inbred C57BL
Mice, Knockout
Multigene Family--drug effects
Tolbutamide--metabolism