Oulès, Bénédicte <br/><br/>
Ryanodine receptor blockade reduces amyloid-β load and memory impairments in Tg2576 mouse model of Alzheimer disease.  [electronic resource] 

 -  The Journal of neuroscience : the official journal of the Society for Neuroscience  Aug 2012 
 - 11820-34 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1529-2401 
<br/><br/><label>Standard No.: </label>10.1523/JNEUROSCI.0875-12.2012  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Alzheimer Disease--complications<br/>Aminophenols--therapeutic use<br/>Amyloid Precursor Protein Secretases--genetics<br/>Amyloid beta-Peptides--metabolism<br/>Amyloid beta-Protein Precursor--genetics<br/>Analysis of Variance<br/>Animals<br/>Brain--cytology<br/>Caffeine--pharmacology<br/>Calcium--metabolism<br/>Calcium Channel Blockers--therapeutic use<br/>Cells, Cultured<br/>Cytosol--drug effects<br/>Dantrolene--pharmacology<br/>Disease Models, Animal<br/>Embryo, Mammalian<br/>Endoplasmic Reticulum--drug effects<br/>Enzyme Inhibitors--therapeutic use<br/>Exploratory Behavior--drug effects<br/>Gene Expression Regulation--drug effects<br/>Humans<br/>Inositol 1,4,5-Trisphosphate Receptors--genetics<br/>Maleimides--therapeutic use<br/>Maze Learning--drug effects<br/>Membrane Potentials--drug effects<br/>Membrane Proteins--metabolism<br/>Memory Disorders--drug therapy<br/>Mice<br/>Mice, Transgenic<br/>Muscle Relaxants, Central--pharmacology<br/>Mutation--genetics<br/>Nerve Tissue Proteins--metabolism<br/>Neuroblastoma--pathology<br/>Neurons--drug effects<br/>Patch-Clamp Techniques<br/>Peptide Fragments--metabolism<br/>Phosphorylation--drug effects<br/>Plaque, Amyloid--metabolism<br/>Purines--therapeutic use<br/>RNA, Messenger--metabolism<br/>Reaction Time--drug effects<br/>Recognition, Psychology--drug effects<br/>Roscovitine<br/>Ryanodine Receptor Calcium Release Channel--genetics<br/>Transfection