TY - GEN AU - Thun,Gian-Andri AU - Ferrarotti,Ilaria AU - Imboden,Medea AU - Rochat,Thierry AU - Gerbase,Margaret AU - Kronenberg,Florian AU - Bridevaux,Pierre-Olivier AU - Zemp,Elisabeth AU - Zorzetto,Michele AU - Ottaviani,Stefania AU - Russi,Erich W AU - Luisetti,Maurizio AU - Probst-Hensch,Nicole M TI - SERPINA1 PiZ and PiS heterozygotes and lung function decline in the SAPALDIA cohort SN - 1932-6203 PY - 2013///0423 KW - Adolescent KW - Adult KW - Air Pollution KW - adverse effects KW - Airway Obstruction KW - epidemiology KW - Alleles KW - Cohort Studies KW - Female KW - Follow-Up Studies KW - Genotype KW - Heart Diseases KW - Heterozygote KW - Humans KW - Longitudinal Studies KW - Lung KW - enzymology KW - Male KW - Middle Aged KW - Protease Inhibitors KW - metabolism KW - Proteolysis KW - Reproducibility of Results KW - Spirometry KW - Young Adult KW - alpha 1-Antitrypsin KW - genetics KW - alpha 1-Antitrypsin Deficiency N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1371/journal.pone.0042728 ER -