TY  - GEN
AU  - Khodzhigorova,Aisa
AU  - Distler,Alfiya
AU  - Lang,Veronika
AU  - Dees,Clara
AU  - Schneider,Holm
AU  - Beyer,Christian
AU  - Gelse,Kolja
AU  - Distler,Oliver
AU  - Schett,Georg
AU  - Distler,Jörg H W
TI  - Inhibition of sumoylation prevents experimental fibrosis
SN  - 1468-2060
PY  - 2012///1220
KW  - Adolescent
KW  - Adult
KW  - Animals
KW  - Disease Models, Animal
KW  - Female
KW  - Fibroblasts
KW  - drug effects
KW  - Fibrosis
KW  - prevention & control
KW  - Gene Knockdown Techniques
KW  - Humans
KW  - Immunosuppressive Agents
KW  - therapeutic use
KW  - Keratinocytes
KW  - metabolism
KW  - Male
KW  - Methotrexate
KW  - Mice
KW  - Middle Aged
KW  - RNA, Small Interfering
KW  - genetics
KW  - Receptors, Transforming Growth Factor beta
KW  - SUMO-1 Protein
KW  - Scleroderma, Systemic
KW  - Signal Transduction
KW  - Skin
KW  - pathology
KW  - Smad3 Protein
KW  - Sumoylation
KW  - physiology
KW  - Ubiquitin-Conjugating Enzymes
KW  - Young Adult
KW  - Ubiquitin-Conjugating Enzyme UBC9
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1136/annrheumdis-2012-201746
ER  -