TY  - GEN
AU  - Kim,Young B
AU  - Balasis,Maria E
AU  - Doi,Kenichiro
AU  - Berndt,Norbert
AU  - DuBoulay,Courtney
AU  - Hu,Chih-Chi Andrew
AU  - Guida,Wayne
AU  - Wang,Hong-Gang
AU  - Sebti,Saïd M
AU  - Del Valle,Juan R
TI  - Synthesis and evaluation of substituted hexahydronaphthalenes as novel inhibitors of the Mcl-1/BimBH3 interaction
SN  - 1464-3405
PY  - 2013///0104
KW  - Antineoplastic Agents
KW  - chemistry
KW  - Apoptosis Regulatory Proteins
KW  - antagonists & inhibitors
KW  - Bcl-2-Like Protein 11
KW  - Cell Proliferation
KW  - drug effects
KW  - Dose-Response Relationship, Drug
KW  - Drug Screening Assays, Antitumor
KW  - Enzyme-Linked Immunosorbent Assay
KW  - Humans
KW  - Membrane Proteins
KW  - Models, Molecular
KW  - Molecular Conformation
KW  - Myeloid Cell Leukemia Sequence 1 Protein
KW  - Naphthalenes
KW  - chemical synthesis
KW  - Protein Binding
KW  - Proto-Oncogene Proteins
KW  - Proto-Oncogene Proteins c-bcl-2
KW  - Structure-Activity Relationship
KW  - Tumor Cells, Cultured
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1016/j.bmcl.2012.07.050
ER  -