TY - GEN AU - Deogracias,Rubén AU - Yazdani,Morteza AU - Dekkers,Martijn P J AU - Guy,Jacky AU - Ionescu,Mihai Constantin S AU - Vogt,Kaspar E AU - Barde,Yves-Alain TI - Fingolimod, a sphingosine-1 phosphate receptor modulator, increases BDNF levels and improves symptoms of a mouse model of Rett syndrome SN - 1091-6490 PY - 2012///1211 KW - Animals KW - Astrocytes KW - cytology KW - Brain-Derived Neurotrophic Factor KW - deficiency KW - Cell Death KW - drug effects KW - Cells, Cultured KW - Disease Models, Animal KW - Excitatory Amino Acid Agonists KW - toxicity KW - Female KW - Fingolimod Hydrochloride KW - Immunosuppressive Agents KW - pharmacology KW - MAP Kinase Signaling System KW - Methyl-CpG-Binding Protein 2 KW - genetics KW - Mice KW - Motor Activity KW - N-Methylaspartate KW - Neurons KW - Organ Culture Techniques KW - Pregnancy KW - Propylene Glycols KW - Receptors, Lysosphingolipid KW - agonists KW - Rett Syndrome KW - drug therapy KW - Sphingosine KW - analogs & derivatives N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1073/pnas.1206093109 ER -