Deogracias, Rubén <br/><br/>
Fingolimod, a sphingosine-1 phosphate receptor modulator, increases BDNF levels and improves symptoms of a mouse model of Rett syndrome.  [electronic resource] 

 -  Proceedings of the National Academy of Sciences of the United States of America  Aug 2012 
 - 14230-5 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1091-6490 
<br/><br/><label>Standard No.: </label>10.1073/pnas.1206093109  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Astrocytes--cytology<br/>Brain-Derived Neurotrophic Factor--deficiency<br/>Cell Death--drug effects<br/>Cells, Cultured<br/>Disease Models, Animal<br/>Excitatory Amino Acid Agonists--toxicity<br/>Female<br/>Fingolimod Hydrochloride<br/>Immunosuppressive Agents--pharmacology<br/>MAP Kinase Signaling System--drug effects<br/>Methyl-CpG-Binding Protein 2--genetics<br/>Mice<br/>Motor Activity--drug effects<br/>N-Methylaspartate--toxicity<br/>Neurons--cytology<br/>Organ Culture Techniques<br/>Pregnancy<br/>Propylene Glycols--pharmacology<br/>Receptors, Lysosphingolipid--agonists<br/>Rett Syndrome--drug therapy<br/>Sphingosine--analogs & derivatives