TY  - GEN
AU  - Geng,Hui
AU  - Lan,Rongpei
AU  - Singha,Prajjal K
AU  - Gilchrist,Annette
AU  - Weinreb,Paul H
AU  - Violette,Shelia M
AU  - Weinberg,Joel M
AU  - Saikumar,Pothana
AU  - Venkatachalam,Manjeri A
TI  - Lysophosphatidic acid increases proximal tubule cell secretion of profibrotic cytokines PDGF-B and CTGF through LPA2- and Gαq-mediated Rho and αvβ6 integrin-dependent activation of TGF-β
SN  - 1525-2191
PY  - 2013///0206
KW  - Animals
KW  - Antigens, Neoplasm
KW  - metabolism
KW  - Cell Nucleus
KW  - drug effects
KW  - Connective Tissue Growth Factor
KW  - genetics
KW  - Cytokines
KW  - Fibrosis
KW  - GTP-Binding Protein alpha Subunits, Gq-G11
KW  - Gene Expression Regulation
KW  - Humans
KW  - Integrins
KW  - Kidney Tubules, Proximal
KW  - Lipids
KW  - blood
KW  - Lysophospholipids
KW  - pharmacology
KW  - Male
KW  - Mice
KW  - Proto-Oncogene Proteins c-sis
KW  - RNA, Messenger
KW  - Rats
KW  - Rats, Sprague-Dawley
KW  - Receptors, Lysophosphatidic Acid
KW  - Regeneration
KW  - Reperfusion Injury
KW  - Signal Transduction
KW  - Smad2 Protein
KW  - Time Factors
KW  - Transforming Growth Factor beta
KW  - rho GTP-Binding Proteins
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural
UR  - https://doi.org/10.1016/j.ajpath.2012.06.035
ER  -