Geng, Hui <br/><br/>
Lysophosphatidic acid increases proximal tubule cell secretion of profibrotic cytokines PDGF-B and CTGF through LPA2- and Gαq-mediated Rho and αvβ6 integrin-dependent activation of TGF-β.  [electronic resource] 

 -  The American journal of pathology  Oct 2012 
 - 1236-49 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, N.I.H., Extramural 
<br/><br/><label>ISSN: </label>1525-2191 
<br/><br/><label>Standard No.: </label>10.1016/j.ajpath.2012.06.035  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Antigens, Neoplasm--metabolism<br/>Cell Nucleus--drug effects<br/>Connective Tissue Growth Factor--genetics<br/>Cytokines--genetics<br/>Fibrosis<br/>GTP-Binding Protein alpha Subunits, Gq-G11--metabolism<br/>Gene Expression Regulation--drug effects<br/>Humans<br/>Integrins--metabolism<br/>Kidney Tubules, Proximal--drug effects<br/>Lipids--blood<br/>Lysophospholipids--pharmacology<br/>Male<br/>Mice<br/>Proto-Oncogene Proteins c-sis--genetics<br/>RNA, Messenger--genetics<br/>Rats<br/>Rats, Sprague-Dawley<br/>Receptors, Lysophosphatidic Acid--metabolism<br/>Regeneration--drug effects<br/>Reperfusion Injury--metabolism<br/>Signal Transduction--drug effects<br/>Smad2 Protein--metabolism<br/>Time Factors<br/>Transforming Growth Factor beta--metabolism<br/>rho GTP-Binding Proteins--metabolism