TY - GEN AU - Haaß,Wiltrud AU - Stehle,Michael AU - Nittka,Stefanie AU - Giehl,Michelle AU - Schrotz-King,Petra AU - Fabarius,Alice AU - Hofmann,Wolf-Karsten AU - Seifarth,Wolfgang TI - The proteolytic activity of separase in BCR-ABL-positive cells is increased by imatinib SN - 1932-6203 PY - 2013///0219 KW - Antineoplastic Agents KW - pharmacology KW - Benzamides KW - Blast Crisis KW - drug therapy KW - Cell Cycle Proteins KW - genetics KW - Cyclin B1 KW - Drug Resistance, Neoplasm KW - drug effects KW - Endopeptidases KW - Fusion Proteins, bcr-abl KW - Genomic Instability KW - HL-60 Cells KW - Humans KW - Imatinib Mesylate KW - K562 Cells KW - Leukemia, Myelogenous, Chronic, BCR-ABL Positive KW - Neoplasm Proteins KW - Phosphorylation KW - Piperazines KW - Protein Phosphatase 2 KW - Proteolysis KW - Pyrimidines KW - Securin KW - Separase KW - U937 Cells N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1371/journal.pone.0042863 ER -