TY - GEN AU - Shao,Y AU - Aplin,A E TI - BH3-only protein silencing contributes to acquired resistance to PLX4720 in human melanoma SN - 1476-5403 PY - 2013///0417 KW - Adaptor Proteins, Signal Transducing KW - genetics KW - Apoptosis KW - drug effects KW - Apoptosis Regulatory Proteins KW - Bcl-2-Like Protein 11 KW - Cell Line, Tumor KW - Drug Resistance, Neoplasm KW - G1 Phase Cell Cycle Checkpoints KW - Histone Deacetylases KW - chemistry KW - Humans KW - Hydroxamic Acids KW - pharmacology KW - Indoles KW - toxicity KW - Melanoma KW - metabolism KW - Membrane Proteins KW - Mitogen-Activated Protein Kinase 1 KW - Mitogen-Activated Protein Kinase 3 KW - Proto-Oncogene Proteins KW - Proto-Oncogene Proteins B-raf KW - Proto-Oncogene Proteins c-bcl-2 KW - S Phase Cell Cycle Checkpoints KW - Sulfonamides KW - Up-Regulation KW - Vemurafenib KW - Vorinostat N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural UR - https://doi.org/10.1038/cdd.2012.94 ER -