TY  - GEN
AU  - Jones,Deuan C
AU  - Alphey,Magnus S
AU  - Wyllie,Susan
AU  - Fairlamb,Alan H
TI  - Chemical, genetic and structural assessment of pyridoxal kinase as a drug target in the African trypanosome
SN  - 1365-2958
PY  - 2013///0130
KW  - Amino Acid Sequence
KW  - Animals
KW  - Antiprotozoal Agents
KW  - pharmacology
KW  - Disease Models, Animal
KW  - Enzyme Inhibitors
KW  - Gene Deletion
KW  - Genes, Essential
KW  - Genes, Protozoan
KW  - Humans
KW  - Kinetics
KW  - Mice
KW  - Models, Molecular
KW  - Molecular Sequence Data
KW  - Phosphorylation
KW  - Protein Conformation
KW  - Pyridoxal
KW  - metabolism
KW  - Pyridoxal Kinase
KW  - antagonists & inhibitors
KW  - Pyridoxamine
KW  - Pyridoxine
KW  - analogs & derivatives
KW  - Sequence Alignment
KW  - Survival Analysis
KW  - Trypanosoma brucei brucei
KW  - enzymology
KW  - Trypanosomiasis, African
KW  - mortality
KW  - Virulence Factors
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1111/j.1365-2958.2012.08189.x
ER  -