TY  - GEN
AU  - Koziolek,Eva J
AU  - Donoghue,Jacqueline F
AU  - Bentley,John D
AU  - Lovrecz,George
AU  - Dolezal,Olan
AU  - Ward,Colin W
AU  - Rothacker,Julie
AU  - Nice,Edouard C
AU  - Burgess,Antony W
AU  - Hafner,M
AU  - Johns,Terrance G
AU  - Adams,Timothy E
TI  - A high-affinity ErbB4Fc fusion protein is a potent antagonist of heregulin-mediated receptor activation
SN  - 1029-2292
PY  - 2013///0404
KW  - Animals
KW  - Betacellulin
KW  - Breast Neoplasms
KW  - drug therapy
KW  - CHO Cells
KW  - Cell Line
KW  - Cricetinae
KW  - ErbB Receptors
KW  - genetics
KW  - Extracellular Signal-Regulated MAP Kinases
KW  - antagonists & inhibitors
KW  - Female
KW  - HEK293 Cells
KW  - Humans
KW  - I-kappa B Proteins
KW  - Immunoglobulin G
KW  - Intercellular Signaling Peptides and Proteins
KW  - metabolism
KW  - JNK Mitogen-Activated Protein Kinases
KW  - MCF-7 Cells
KW  - Melanoma
KW  - pathology
KW  - Mice
KW  - Neuregulin-1
KW  - Ovarian Neoplasms
KW  - Phosphorylation
KW  - Proto-Oncogene Proteins c-akt
KW  - Receptor, ErbB-4
KW  - Receptors, Fc
KW  - Recombinant Fusion Proteins
KW  - Signal Transduction
KW  - Xenograft Model Antitumor Assays
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.3109/08977194.2012.709516
ER  -