Pannaccione, Anna

A new concept: Aβ1-42 generates a hyperfunctional proteolytic NCX3 fragment that delays caspase-12 activation and neuronal death. [electronic resource] - The Journal of neuroscience : the official journal of the Society for Neuroscience Aug 2012 - 10609-17 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1529-2401

10.1523/JNEUROSCI.6429-11.2012 doi


Amyloid beta-Peptides--pharmacology
Animals
Calcium--metabolism
Calcium Channel Blockers--pharmacology
Calpain--metabolism
Caspase 3--metabolism
Cell Death--drug effects
Cell Differentiation--drug effects
Cells, Cultured
Chelating Agents--pharmacology
Cricetinae
Dogs
Dose-Response Relationship, Drug
Egtazic Acid--pharmacology
Embryo, Mammalian
Endoplasmic Reticulum--drug effects
Enzyme Activation--drug effects
Female
Hippocampus--cytology
Male
Mice
Mice, Knockout
Nerve Growth Factor--pharmacology
Neurons--drug effects
Patch-Clamp Techniques
Peptide Fragments--pharmacology
Proteolysis--drug effects
RNA Interference--physiology
Rats
Sodium--metabolism
Sodium-Calcium Exchanger--genetics
Time Factors
Transfection
Up-Regulation--drug effects