Furanodiene, a natural product, inhibits breast cancer growth both in vitro and in vivo. [electronic resource]
- Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2012
- 778-90 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1421-9778
10.1159/000341457 doi
Amino Acid Chloromethyl Ketones--pharmacology Animals Antineoplastic Agents, Phytogenic--therapeutic use Apoptosis--drug effects Breast Neoplasms--drug therapy Caspase 7--metabolism Caspase 9--metabolism Cell Line, Tumor Cell Proliferation--drug effects Curcuma--chemistry DNA Fragmentation--drug effects Female Furans--therapeutic use G1 Phase Cell Cycle Checkpoints--drug effects Heterocyclic Compounds, 2-Ring--therapeutic use Humans L-Lactate Dehydrogenase--metabolism MCF-7 Cells Membrane Potential, Mitochondrial--drug effects Mice Mice, Inbred BALB C Mice, Nude Poly(ADP-ribose) Polymerases--metabolism Proto-Oncogene Proteins c-akt--antagonists & inhibitors Transplantation, Heterologous bcl-2-Associated X Protein--metabolism bcl-Associated Death Protein--metabolism