Clinch, Keith <br/><br/>
Transition state analogue inhibitors of human methylthioadenosine phosphorylase and bacterial methylthioadenosine/S-adenosylhomocysteine nucleosidase incorporating acyclic ribooxacarbenium ion mimics.  [electronic resource] 

 -  Bioorganic & medicinal chemistry  Sep 2012 
 - 5181-7 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1464-3391 
<br/><br/><label>Standard No.: </label>10.1016/j.bmc.2012.07.006  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Adenosine--analogs & derivatives<br/>Biomimetic Materials--chemical synthesis<br/>Dose-Response Relationship, Drug<br/>Enzyme Inhibitors--chemical synthesis<br/>Escherichia coli--enzymology<br/>Humans<br/>Ions--chemical synthesis<br/>Molecular Conformation<br/>N-Glycosyl Hydrolases--antagonists & inhibitors<br/>Neisseria meningitidis--enzymology<br/>Purine-Nucleoside Phosphorylase--antagonists & inhibitors<br/>Pyrrolidines--chemical synthesis<br/>Structure-Activity Relationship